世界*实验材料供应商TriLink BioTechnologies, Inc正式授权苏州蚂蚁淘为其中国代理，TriLink BioTechnologies, Inc在一直是行业的标杆,一直为广大科研客户提供zui为优质的产品和服务,苏州蚂蚁淘一直秉承为中国科研客户带来的产品，的服务，签约TriLink BioTechnologies, Inc就是为了给广大科研客户带来更加完善的产品和服务,您的满意将是我们zui大的收获
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TriLink BioTechnologies 高品质常规/特殊核苷酸产品*
TriLink BioTechnologies公司是世界著名的核酸修饰技术领域的*，成立于1996年，总部设在San Diego，California。TriLink公司致力于高品质核酸修饰产品的研发和生产，提供包括核苷酸、常规及核苷三磷酸特殊修饰的寡核苷酸定制（oligonucleotides），m RNA合成，CleanAmp?PCR产品，phosphoramidites和其他小分子在内的众多产品。近二十年来，TriLink一直是诊断和OEM市场核酸产品供应的行业*，产品应用于基因治疗，核苷类化疗，寡核苷酸治疗和诊断领域。此外，TriLink还可提供特殊核苷酸、m RNA定制，合同研究服务和ISO/ QSR标准的cGMP生产设施。TriLink完善的产品及研发服务解决方案有助于推动药物发现和生物医学研究。
经过18年的发展， TriLink已经成为高品质RNA合成领域的*，为广大科研工作者提供优质的mRNA及长链RNA（长可达几个Kb），并且定制修饰。同时我们也提供成品mRNA产品，包括报告基因及 mRNA表达因子。
Genome Editing mRNAPlasmids and viral vectors have traditionally been used in genome editing to express the required proteins inside cells or an organism. However, editing DNA carries a risk. Double stranded DNA breaks catalyze insertion of DNA at the cut site. At some substantial frequency, the protein expression vectors can integrate, which can lead to continuous expression of the nuclease or a previously silent sequence.
Now mRNA is being used in genome editing to transiently express the required proteins. With no risk of insertional mutagenesis, it is a powerful tool. Additionally synthetic mRNA, which mimics fully processed, capped and polyadenylated mRNA, can be produced in large quantities byin vitrotranscription and modified to reduce innate immune stimulation.
产品如下：
货号品名规格价格品牌GenomeEditingmRNAL-7206CleanCap Cas9mRNA(modified)20 grams2550TriLinkBioTechnologiesL-7206CleanCap Cas9mRNA(modified)100 grams6035TriLinkBioTechnologiesL-7206CleanCap Cas9mRNA(modified)1mg31875TriLinkBioTechnologiesL-7206CleanCap Cas9mRNA(modified)5mg(5x1mg)114750TriLinkBioTechnologiesL-7211CleanCap CremRNA(5moU)5moU询价TriLinkBioTechnologiesL-7207CleanCap Cas9NickasemRNA(5moU)20 grams2550TriLinkBioTechnologiesL-7207CleanCap Cas9NickasemRNA(5moU)100 grams6035TriLinkBioTechnologiesL-7207CleanCap Cas9NickasemRNA(5moU)1mg31875TriLinkBioTechnologiesL-7207CleanCap Cas9NickasemRNA(5moU)5mg(5x1mg)114750TriLinkBioTechnologiesL-7606CleanCap Cas9mRNA20 grams2125TriLinkBioTechnologiesL-7606CleanCap Cas9mRNA100 grams5015TriLinkBioTechnologiesL-7606CleanCap Cas9mRNA1mg26775TriLinkBioTechnologiesL-7606CleanCap Cas9mRNA5mg(5x1mg)96050TriLinkBioTechnologiesZinc-finger Nuclease mRNA (ZFN mRNA)
Zinc-finger nucleases (ZFNs) were the first widely applicable site specific genome editing tools. Recently, several studies have shown that ZFNs can have off-target effects at non-targeted chromosomal sites that are similar in sequence to the intended target site. For this reason, there is a move to transient ZFN expression using mRNA based vectors. TriLink s custom mRNA transcription service includes ZFN mRNA. Request a quote today!
![](\"https://www.trilinkbiotech.com/gif/ZFN.gif\")
L-7206CleanCap Cas9 mRNA (modified)CleanCap CRISPR Associated Protein 9 mRNA (U-modified)
mRNA Length:4,521 nucleotides
Concentration:1.0 mg/mL
Buffer:1 mM Sodium Citrate, pH 6.4
Identity Purity:
Agarose Gel Mobility;Pass
Concentration 5%;Pass
Product InsertSDS
Cas9 mRNA expresses a version of theStreptococcus pyogenesSF370 Cas9 protein (CRISPR Associated Protein 9). Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform double stranded DNA cleavage.
Cas9 mRNA encodes the Cas9 protein with an N and C terminal nuclear localization signal (NLS). The incorporation of two NLS signals within the mRNA increases the frequency of delivery to the nucleus, thus increasing the rate of DNA cleavage. Additionally, a C terminal HA epitope tag aids detection, isolation, and purification of the Cas9 protein.
This mRNA is capped using CleanCap , TriLink s proprietary co-transciptional capping method, which results in the naturally occuring Cap 1 structure with high capping efficiency. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.
Certificate(s) of Analysis
TD-OA02A
T1-CHZ01A-1
L-7206 is a replacement product for L-6125 and L-6129.
Not for resale without express written permission. Not for use in humans. No license under any patent or patent pending is granted or implied by the purchase of any TriLink product. TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser s sole responsibility.
CleanCap Cre mRNA (5moU)CleanCap NLS-Cre Recombinase mRNA(5-methoxyuridine)
Contact us today to preorder!
Catalog Number:L-7211
mRNA Length:1,437 nucleotides
Concentration:1.0 mg/mL
Buffer:1 mM Sodium Citrate, pH 6.4
Identity Purity:
Agarose Gel Mobility;Pass
Concentration 5%;Pass
Product InsertSDS
NLS-Cre Recombinase mRNA is a capped and polyadenylated messenger RNA encoding Cre recombinase fused to a nuclear localization sequence (NLS). Cre recombinase is a tyrosine recombinase that catalyzes recombination between two loxP sites.
This mRNA is capped using CleanCap , TriLink s proprietary co-transciptional capping method, which results in the naturally occuring Cap 1 structure with high capping efficiency. It is polyadenylated, modified with 5-methoxyuridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.
L-7211 is a replacement for L-6108.
Not for resale without express written permission. Not for use in humans. No license under any patent or patent pending is granted or implied by the purchase of any TriLink product. TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser s sole responsibility.
L-7606CleanCap Cas9 mRNACleanCap CRISPR Associated Protein 9 mRNAmRNA Length:4,521 nucleotides
Concentration:1.0 mg/mL
Buffer:1 mM Sodium Citrate, pH 6.4
Identity Purity:
Agarose Gel Mobility;Pass
Concentration 5%;Pass
Product InsertSDS
Cas9 mRNA expresses a version of theStreptococcus pyogenesSF370 Cas9 protein (CRISPR Associated Protein 9). Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform double stranded DNA cleavage.
Cas9 mRNA encodes the Cas9 protein with an N and C terminal nuclear localization signal (NLS). The incorporation of two NLS signals within the mRNA increases the frequency of delivery to the nucleus, thus increasing the rate of DNA cleavage. Additionally, a C terminal HA epitope tag aids detection, isolation, and purification of the Cas9 protein.
This mRNA is capped using CleanCap , TriLink s proprietary co-transciptional capping method, which results in the naturally occuring Cap 1 structure with high capping efficiency. It is polyadenylated, and optimized for mammalian systems. It mimics a fully processed mature mRNA.
我们公司zui大优势是强大的采购，
1：基本什么都能进口，血清，抗体，耗材，还有部分限制进口的，
2：货品全，现经营过700多个品牌，基本所有生物试剂耗材都可以进口，特别是冷偏的产品那就更有优势，
3：提供加急服务，一般1-2周到货，超过时限加急费全免
4：价格公道，绝大部分价格有优势，当然不能保证100%产品都是价格zui低,因为价格zui低意味着没有服务.
5：良好的信誉，大部分客户我们提供货到付款服务，客户包括清华，北大交大复旦，中山等100多所大学，ROCHE，阿斯利康，国药，fisher等500多家公司
6：我们还是Santa,Advanced Biotechnologies Inc, Sarstedt ,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. Dako,Inc, GePromegaridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,Sarstedt , Polysciences,prospecbi, QA-BIO,quickzyme,FULLERLABS,INC,sterlitech；sysy,TriLink BioTechnologies,Inc；worthington-biochem,zyagen等几十家国外公司授权代理。7：我们还是invitrogen,qiagen,Sarstedt am,sigma;Promega,roche,merck, rnd,BD, GE,pierce,BioLegend等知名大品牌批发，欢迎合作。
苏州蚂蚁淘实验试剂有限公司：办公：: 地址：上海市浦东新区晨阳路225弄东方现代商业广场46号303室(近东亭路)
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